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If cancer researchers ever had a collective 'Stand-with-your-mouth-wide-open in shock' moment, it's now.
What causes cancer and who survives it?
The most comprehensive approach to what cancer is and how to treat it.
For more than 10 years, Lothar Hirneise has traveled the world looking for the most successful cancer therapies, He has been the president of Cancer 21 since 1997, an organisation for research and documentation of holistic cancer therapies with approximately. 2.000 members worldwide. He is the author of the bestseller book: Chemotherapy heals cancer and the world is flat and director of the 3E-center in Germany. For many years he is teaching worldwide the 3E program, which is based on the analysis of case histories of thousands of people who survived late stage cancer. Learn why so many people die of cancer, and why so many others do not.
Something is Very Wrong
For over 50 years researchers have been hunting down, cataloging, and developing drugs to combat the genetic mutations thought to cause cancer – with remarkably little success. Enormous amounts of time and money have been spent on cancer research yet contradictions, confusion, and frustration continue to dominate the landscape of the field.
What is The Metabolic Theory
Put simply, the metabolic theory states that cancer originates from damage to the cell’s capacity to generate energy with oxygen (oxidative energy production), with a concurrent increase in energy generation without oxygen.
The metabolic theory of cancer is not a new theory. It was first proposed by Nobel Prize winning German biochemist Otto Warburg in 1924. The theory was subsequently discarded when it was discovered that cancer cells had mutations to DNA, the profound new molecule Watson and Crick had just reveled to the world.
A healthy cell produces 89% of its energy using oxygen
11% through non-oxidative metabolism (non-oxidative metabolism is also known as “fermentation”).
Oxidative energy production is far more efficient than fermentation.
Almost 20 times more energy is released when glucose is completely oxidized, as opposed to when it is fermented.
Oxidative energy production takes place in a cellular organelle called the mitochondria also known as the cellular “power plant.”
The metabolic theory of cancer contends that cancer begins with damage to the mitochondria.
The cell is then forced to shift energy production to fermentation in order to survive. It is telling that this one feature of cancer, damaged mitochondria and increased fermentation is present in all cancer types.
Also telling is the fact that the greater the degree of fermentation displayed by a given cancer, the more aggressive the cancer.
Because a tumor cell’s mitochondria are damaged, and are therefore forced to generate energy by such an inefficient pathway, they have to consume much more glucose to remain viable.
A glance at a PET scan, which uses a radioactive labeled glucose analog to image cancer, provides stunning visual evidence of the voracious appetite tumor cells have for glucose compared to normal tissue.
Emerging evidence suggests that all of the hallmarks of cancer can be explained by mitochondrial damage followed by a shift to non-oxidative energy metabolism.
Once the oxidative energy generating capacity of the cell is impaired, the cell undergoes a dramatic transformation; important oncogenes (cancer causing genes) are switched on, initiating the uncontrolled proliferation that is the hallmark of the disease.
Some degree of metabolic dysfunction has been shown to be present in every type of cancer, regardless of tissue of origin.
The latest push by the NCI is called the Cancer Genome Atlas Project. Its stated mission: “To systematically explore the entire spectrum of genomic changes involved in more than 20 types of human cancer.” The goal of this ambitious project is to once and for all, find and sequence all of the genetic mutations responsible for cancer.
But so far the search for causative mutations has remained elusive – in fact, to date, the data suggests that mutations may not be involved in ways previously assumed. The genetic mutational profile of any given cancer type looks different from person to person, rendering it impossible to claim mutations are definitely responsible for the origin of the disease. To be sure, some genes are mutated more frequently than others, but it appears that no single gene, or even any combination of genes, is absolutely necessary for the development of a tumor within a person. And to make things even more confusing, the mutational profile is different from cell to cell within the same tumor, rendering development of drugs that target mutations next to impossible. The drug targets not only change from person to person, but even within the tumor of a single individual.
One Single Comprehensive Theory
It is well established that once a cell has an impaired ability to produce energy through oxidative pathways, the genomic instability (increased potential for DNA mutations to occur) that accompanies tumor development, inevitable follows. While the genetic mutations acquired following mitochondrial impairment unquestionably contribute to the tumor cell’s qualitative features and aggressiveness, experimental evidence is unable to unequivocally assign them as the origin of the disease. The metabolic theory contends that mutations to DNA are of secondary consequence, or an epiphenomenon to the true cause, metabolic dysfunction.
While it’s true that most of the agents known to cause cancer; chemical carcinogens, viruses, radiation, and inflammation can cause mutations to DNA, it is also true these provocative agents damage the mitochondria. The metabolic theory of cancer states that once the mitochondria of a given cell acquire a threshold degree of damage, and the cell reverts to fermentation to obtain energy, cancer has begun.
Inherited Cancer Risk fits the Metabolic Theory
Many of you have probably heard of BRCA1. An inherited version of BRCA1 can increase a women’s risk of developing breast cancer by up to 60%. Even though genes like BRCA1 receive a lot of press and evoke fears of the inevitability of cancer, only 5 to 7% of all cancers are attributed to the genes inherited from your mother and father – most cancers arise spontaneously. An inherited predisposition to develop cancer has been historically cited as evidence that cancer is a genetic disease – and it certainly appears that way at first glance. However, an exhaustive look at these rare inherited mutations reveal that all of them also increase the propensity of the cell to incur mitochondrial damage – leading to impaired oxidative energy production – the hallmark of the metabolic theory.
It is certainly true that all scientific endeavors are not created equal, and some experiments provide a more profound understanding of the physical world compared to others. An elegant series of nuclear/cytoplasm transfer experiments fall into this esteemed category, and are exceptionally important in revealing important qualities of the disease.
In brief, the experiments consist of transferring the nucleus (this is where the DNA resides) of a cancer cell into a healthy cell that has had its nucleus removed prior. The newly created hybrid cell has the genetic material of a cancer cell, with all of its defects, but now has the healthy mitochondria of a normal cell. Intuitively, if the origin of cancer stems solely from mutations to DNA, the newly created hybrid cells, that still retain all of the mutations, should be tumorigenic. But they are not. They are perfectly healthy. These experiments were carefully executed, with strict controls, and were found to be very reproducible. Experiments like these provide strong evidence that damaged mitochondria appear to be the driving force behind malignancy.
Just getting started
The therapeutic implications of the metabolic theory of cancer are enormous. It opens up profound possibilities for new avenues of treatment. Without question the metabolic therapeutic approaches explored so far have exhibited tremendous promise. The first and most obvious place to start is by implementing a ketogenic diet, starving the cancer cells of the glucose they so heavily rely on for survival. The preclinical results have been remarkably consistent. In virtually every experiment in which the ketogenic diet has been tested in mice, tumor growth rates have slowed dramatically. The results of the diet stand alone, but the results get really exciting when the diet is utilized in addition to other therapies. It appears that the ketogenic diet is able to put cancer cells under significant metabolic stress allowing addition therapies, like cisplatin, radiation, and hyperbaric -oxygen to push the cells over the edge, increasing their efficacy exponentially. And this is just scratching the surface. So much remains to be done.
We don’t want to sit on our hands waiting any longer.
An electron microscope image showing the location of BRCA1 within the mitochondria.
A diagram summarizing a series of experiments conclusively determining that it is the mitochondria, and not nuclear DNA, that causes cancer.
LEFT: Healthy Mitochondria. Note the abundant looping structures inside the mitochondria (cristae), this is where all energy is produced through oxidative pathways.
MIDDLE: Image of a mitochondria from a cancer cell. Note the almost complete absence of cristae
RIGHT: PET scan showing widespread metastasis
Diagram showing the progression of cancer. Once a threshold degree of mitochondrial damage occurs uncontrolled proliferation begins. The different colors depict cells with different mutational profiles within the same tumor. If a drug is developed targeting a specific mutation, the presence of sub clonal populations with different mutations will most likely render it ineffectual.
I would add that the other vitally important aspect which affects the health of our mitochondria and therefore our cells is our emotions, thoughts / state of mind. Read this section on our thinking to see how thoughts produce chemicals that directly effect cellular health and activity, as well as a state of contraction in our body, our breath and choices.
Supporting the metabolic approach, many brilliant scientists have designed protocols. Despite their rejection by mainstream medicine,
many using them can testify to their efficacy. We will look at some of them:
Cottage cheese / Quark
The Budwig Protocol
The Budwig Protocol was named after Johanna Budwig (seven-time Nobel Prize nominee.), a German biochemist, pharmacologist and physicist. Dr. Budwig discovered (or perhaps simply confirmed) that most saturated fats are nutritionally “dead” - they not only fail to nourish but also end up destroying the electrical charge of the cells of the human body. Without this electrical charge, the cells are not able to assimilate oxygen, and so, quite literally, suffocate.
More specifically, such saturated fats are “dead” in the sense that they don’t contain pi-electrons, which function like cellular spark-plugs, allowing the cells to “breathe” properly – to assimilate and transport oxygen – as well as to detoxify cellular waste. As the body accumulates larger and larger numbers of functionally dead cells, the resulting de-oxygenated and toxic cellular environment becomes ripe for various forms of physical dis-ease. So this pretty much defined the “problem,” as Dr. Budwig saw it.
Dr. Budwig also knew that the best source of the pi-electrons needed for proper cellular oxygenation was in two essential fatty acids found in flaxseed oil. She knew that these essential fatty acids could both re-oxygenate the cells as well as repair their lipid membranes. The conundrum was that only water-soluble solutions are able to enter cells directly, and oils are not water-soluble. So, while flaxseed oil contained the medicine (aka the essential fatty acids) that the cells most needed, there was no obvious way to make it immediately available to the cells.
Johanna Budwig’s brilliantly simple solution to this conundrum was to combine the flaxseed oil with cottage cheese, whose sulphurated amino acids render the flaxseed oil water-soluble, and so immediately available for use by a human body’s cells. This, then, was the external alchemy that birthed what is now known as the Budwig Protocol.
More background on Budwig
Dr Budwig was born in Germany in 1908. She passed away in 2003 at the age of 95. She has been referred to as a top European Cancer Research Scientist, Biochemist, Blood Specialist, German Pharmacologist, and Physicist. Dr Budwig was a seven-time Nobel Prize nominee.
In Germany in 1952 she was the Central Government’s Senior Expert for fats and pharmaceutical drugs. She’s considered one of the worlds leading authorities on fats and oils. Her research has shown the tremendous effects that commercially processed fats and oils have in destroying cell membranes and lowering the voltage in the cells of our bodies, which then result in chronic and terminal disease. What we have forgotten is that we are body electric.
The cells of our body fire electrically. They have a nucleus in the center of the cell which is positively charged, and the cell membrane, which is the outer lining of the cell, is negatively charged. We are all aware of how bad fats are implicated in the health of our veins and arteries, and are the leading cause of heart attacks, but we never looked beyond the end of our noses to see how these very dangerous fats and oils are affecting the overall health of our minds and bodies at the cellular level.
Dr Budwig discovered that when unsaturated fats have been chemically treated, their unsaturated qualities are destroyed and the field of electrons removed. This Commercial Processing of fats destroys the field of electrons that the cell membranes (60-75 trillion cells) in our bodies must have to fire properly (i.e. function properly).
The fats ability to associate with protein and thereby to achieve water solubility in the fluids of the living body—all this is destroyed. As Dr Budwig put it, “the battery is dead because the electrons in these fats and oils recharge it.” When the electrons are destroyed the fats are no longer active and cannot flow into the capillaries and through the fine capillary networks. This is when circulation problems arise.
Without the proper metabolism of fats in our bodies every vital function and every organ is affected. This includes the generation of new life and new cells. Our bodies produce over 500 million new cells daily. Dr Budwig points out that in growing new cells, there is a dipolarity between the electrically positive nucleus and the electrically negative cell membrane with it’s high unsaturated fatty acids. During cell division the cell and new daughter cell must contain enough electron rich fatty acids in the cells surface area to divide off completely from the old cell. When this process is interrupted the body begins to die. In essence, these commercially processed fats and oils are shutting down the electrical field of the cells allowing chronic and terminal diseases to take hold of our bodies.
A very good example would be tumors. Dr Budwig noted that “The formation of tumors usually happens as follows. In those body areas which normally host many growth processes, such as in the skin and membranes, the glandular organs, for example, the liver and pancreas or the glands in the stomach and intestinal tract—it is here that the growth processes are brought to a stand still. Because the dipolarity is missing, due to the lack of electron rich highly unsaturated fat, the course of growth is disturbed—the surface-active fats are not present; the substance becomes inactive before the maturing and shedding process of the cells ever takes place, which results in the formation of tumors.”
She pointed out that this can be reversed by providing the simple foods, cottage cheese andflax seed oil, which revises the stagnated growth processes. This naturally causes the tumor or tumors present to dissolve and the whole range of symptoms which indicate a “dead battery are cured.” Dr Budwig did not believe in the use of growth-inhibiting treatments such as chemotherapy or radiation. She was quoted as saying “I flat declare that the usual hospital treatments today, in a case of tumorous growth, most certainly leads to worsening of the disease or a speedier death, and in healthy people, quickly causes cancer.”
Dr Budwig discovered that when she combined Flaxseed oil, with its powerful healing nature of essential electron-rich unsaturated fats, and cottage cheese, which is rich in sulfur protein, the chemical reaction produced makes the oil water soluble and easily absorbed into the cell membrane.
I found testimonials of people from around the world who had been diagnosed with terminal cancer (all types of cancer), sent home to die and were now actually cured and living healthy, normal lives. Not only had Dr Budwig been using her protocol for treating cancer in Europe, but she also treated other chronic diseases such as Arthritis, Heart Infarction, Irregular Heart Beat, Psoriasis, Eczema (other skin diseases), Immune Deficiency Syndromes (Multiple Sclerosis and other Auto Immune Diseases), Diabetes, Lungs (respiratory conditions), Stomach Ulcers, Liver, Prostate, Strokes, Brain Tumors, Brain (strengthens activity), Arteriosclerosis and other chronic diseases. Dr Budwig’s protocol proved successful where orthodox traditional medicine was failing.
Let's mind our Mitochondria
CASIE LUKES · OCT 6, 2014
Here are some ways you can improve mitochondrial function and enhance energy and wellness:
Eat less. Animal studies involving a range of species prove that caloric restriction extends lifespan, and population studies suggest that this holds true for humans as well. When you cut back on food consumption, fewer demands are made on your mitochondria, and production of damaging free radicals declines. This not only enhances mitochondrial efficiency, but also turns on SIRT1 genes, which encode proteins that boost cellular function. The result? Better health and a longer life.
Eat right. Switching your diet to low carb, high fat diet, thereby teaching your body to burn fat for energy is the foundation for keeping your mitochondria plentiful, happy, and robust. If you can’t access fat for energy, your cellular power plants will not work as well as they can or should. Any mitochondrial health regimen must include that as a basic precept. Once you’ve firmly established your fat-burning ability, you’ve got to support the body with micronutrients.
Avoiding processed and inflammatory foods is perhaps obvious to most by now, but perhaps less obvious is the types and use of oils (even cold pressed ones), gluten in the form of wheat, barley, rye and oats, and pasteurised dairy rather than raw fermented dairy. More about cancer specific diet in another section.
Exercise more. The stress of physical exercise tunes up existing mitochondria and activates biochemical pathways that stimulate the production of new ones, a phenomenon known as mitochondrial biogenesis. This has been best observed in muscle cells; studies of endurance athletes reveal that their muscles have exceptionally high concentrations of mitochondria. But you don’t have to be a marathon runner to grow new mitochondria. Simply engaging in consistent, moderate aerobic activity stimulates your muscle cells to make this adaptation to increased energy demands. Exercise also forces you to breathe which many of us forget to do enough, during the day. We spend our time in a contracted state, holding our breath, depriving our cells of oxygen!
Discover the mitochondrial-neurological connection as well as a diet to feed your mitochondria here.
Dr. Gene Wei co-authored a book on the Budwig Diet.
Here he discusses some important things you should know before starting the diet and what some of the potential risk factors might be.
Hosh Axe explains
how you can cleanse your colon, detoxify your cells, and heal your cell membrane, using the Budwig Protocol.
He believes this formula, along with the Gerson Therapy are two of the most powerful ways to help heal your body.
The original Budwig formula has three main ingredients, but he's added a few in to create what I call the "Beyond Budwig Protocol."
Cancer researcher who speaks of what are considered 'alternative' treaments are constantly healing people from any type and any stage of cancer. This is done with lifestyle changes and following simple protocols like Budwig.
Sandra Olson, creator of the Yahoo group.
See http://budwig-videos.com for more information on Dr. Johanna Budwig's healing plan
The Budwig Group on Yahoo over 23,000 members